Fig. 1.

Flow diagram demonstrating the number of subjects excluded from analysis and the time points at which they were excluded. *A maximum of 8049 women were included in the univariate analysis, but not all subjects had complete data sets for evaluation. The patients with missing data were excluded from the individual univariate analysis of the variable(s) for which data were missing, but they were included in all analyses of the available variables. The number of women included in the individual analyses ranged from 6153 to 8049. SOF = Study of Osteoporotic Fractures, and BMD = bone mineral density.