TABLE II.
Effect of Risk Factors for Hip Fracture, Adjusted for Age and Total Hip Bone Mineral Density
Risk Factor | No. for Whom Data Available | Hazard Ratio (95% Confidence Interval) | P Value |
---|---|---|---|
Total hip bone mineral density (per 1 standard deviation decrease*) | 8049 | 2.11 (1.94 to 2.29) | <0.001 |
Humeral fracture | 8049 | 1.83 (1.32 to 2.53) | <0.001 |
Non-humeral fracture | 8049 | 1.43 (1.20 to 1.72) | <0.001 |
Height at age of 25 yr (per 10 cm) | 7904 | 1.41 (1.24 to 1.61) | <0.001 |
Depth perception (per 10 times standard deviation of 4 Howard-Dolman optical distance scores) | 7851 | 1.43 (1.13 to 1.82) | 0.003 |
Weight gain since age of 25 yr (per 10 kg) | 7823 | 0.94 (0.85 to 1.04) | 0.2 |
Maternal history of hip fracture after age of 50 yr | 6153 | 1.33 (1.06 to 1.66) | 0.013 |
Estrogen use | 8048 | 1.09 (0.86 to 1.40) | 0.5 |
Use of long-acting benzodiazepines at baseline | 8008 | 0.98 (0.75 to 1.23) | 0.9 |
Self-reported health status (on a scale of 1-5) | 8049 | 1.33 (1.20 to 1.46) | <0.001 |
Walking for exercise | 8049 | 0.85 (0.73 to 0.99) | 0.04 |
Standing or walking <4 hr/day | 8046 | 1.27 (1.04 to 1.55) | 0.02 |
Use of arms to rise from chair | 8046 | 1.37 (1.12 to 1.67) | 0.002 |
History of falls | 8049 | 1.38 (1.18 to 1.61) | <0.001 |
1 standard deviation = 0.133 g/cm2. Total hip bone mineral density was adjusted for age only.