Table 3.
OR and 95 % Confidence Intervals relating the Dementia Diagnosis to the Presence of Heart Abnormalities, adjusted for Age, Gender, Education, Ethnicity, APOE and Potential Vascular Risk Factors, using Controls without Dementia or Stroke as the Reference. There is One Model per Heart Abnormality.
| Vascular dementia (n=9) | Alzheimer's disease (n=18) | Stroke without dementia (n=16)† | |
|---|---|---|---|
| Aortic Valve | |||
| Thickening | 0.8 (0.12-5.61) | 1.4 (0.29-7.14) | 1.3 (0.35-4.57) |
| Regurgitation | 4.2 (0.74-13.29) | 3.3 (1.01-11.88)* | 1.3 (0.31-4.36) |
| Mitral Valve | |||
| Thickening | 4.4 (0.96-18.23) | 3.0 (0.71-12.58) | 0.9 (0.28-3.35) |
| Regurgitation | 0.6 (0.03-10.31) | 0.5 (0.08-3.32) | 1.2 (0.19-6.87) |
| Mitral Annular Calcifications | 2.7 (0.44-16.06) | 1.3 (0.29-5.44) | 3.5 (1.01-9.83)* |
| Tricuspid Valve | |||
| Thickening | 0.5 (0.02-9.06) | 1.3 (0.18-8.51) | 0.9 (0.19-3.99) |
| Regurgitation | -- | 1.4 (0.27-6.78) | 1.4 (0.29-6.56) |
| Pulmonal Valve | |||
| Regurgitation | 1.1 (0.19-6.43) | 0.7 (0.17-2.68) | 0.4 (0.11-1.36) |
| Left Heart | |||
| LV Dilatation | -- | 1.3 (0.06-19.98) | 2.6 (0.31-21.42) |
| reduced LVEF | 3.1 (0.34-39.42) | 4.1 (0.44-9.86) | 4.9 (0.52-33.32) |
| Wall motion abnormalities | 3.3 (0.26-28.57) | 3.6 (0.98-20.35) | 4.6 (0.83-32.42) |
| LV Hypertrophy | 1.3 (0.20-8.11) | 4.5 (1.02-1.99)* | 2.2 (0.56-8.54) |
--
numbers too small for analysis
†
defined according to World Health Organization Criteria.18