Table 3.
Variable | No of patients | No (%) of deaths* | Univariable models | Multivariable model† | |||
---|---|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value‡ | Hazard ratio (95% CI) | P value‡ | ||||
Men | 6228 | 650 (10.4) | 1 | <0.001 | 1 | <0.01 | |
Women | 6602 | 823 (12.5) | 1.22 (1.10 to 1.35) | 0.86 (0.77 to 0.96) | |||
Secondary drug prevention: | |||||||
No | 9864 | 1322 (13.4) | 1 | <0.001 | 1 | <0.001 | |
Yes | 2966 | 151 (5.1) | 0.38 (0.31 to 0.46) | 0.50 (0.42 to 0.59) | |||
Townsend fifth: | |||||||
First (least deprived) | 3159 | 326 (10.3) | 1 | 0.06 | 1 | 0.05 | |
Second | 2829 | 344 (12.2) | 1.20 (1.02 to 1.41) | 1.16 (0.99 to 1.36) | |||
Third | 2719 | 325 (11.9) | 1.18 (0.98 to 1.42) | 1.11 (0.93 to 1.32) | |||
Fourth | 2432 | 268 (11.0) | 1.07 (0.85 to 1.35) | 1.07 (0.88 to 1.30) | |||
Fifth (most deprived) | 1691 | 210 (12.4) | 1.22 (1.00 to 1.50) | 1.29 (1.07 to 1.55) | |||
Age group: | |||||||
50-59 | 1639 | 54 (3.3) | 1 | <0.001 | 1 | <0.001 | |
60-69 | 2749 | 146 (5.3) | 1.63 (1.22 to 2.18) | 1.66 (1.24 to 2.23) | |||
70-79 | 4319 | 407 (9.4) | 2.95 (2.18 to 3.99) | 2.99 (2.20 to 4.06) | |||
80-89 | 3387 | 586 (17.3) | 5.78 (4.23 to 7.91) | 5.63 (4.03 to 7.86) | |||
≥90 | 736 | 280 (38.0) | 14.99 (10.8 to 20.77) | 14.17 (9.91 to 20.26) |
Standard errors adjusted for clustering (113 practices), n=12 830.
*Deaths within 31-365 days of incident stroke.
†Each risk factor (sex, secondary drug prevention, Townsend fifth, age group) adjusted for other factors.
‡Wald test.