Figure 2.
Overlay of 1H-15N TROSY-HSQC spectra of 0.5 mM Mistic in 30 mM DPC micelles in the absence (black) and presence (red) of 10 mM halothane. The spectra were acquired at 30°C. Despite many residues were undisturbed by the addition of halothane, some residues experienced significant chemical shift changes and/or intensity changes of their resonance signals. A few examples are highlighted in small boxes.