Table 1. Demographic data.
NP-BD | SMD | Control | p Value | |
---|---|---|---|---|
N | 39 | 31 | 36 | |
Age (years) | 13.99 ± 2.63 | 12.29 ± 2.12 | 14.34 ± 2.28 | .001 |
Gender (male), % (N) | 53.80 (21) | 61.30 (19) | 55.60 (20) | .81 |
IQ | 110.08 ± 14.15 | 102.74 ± 14.36 | 115.61 ± 14.21 | .002 |
CGAS | 48.95 ± 12.41 | 47.50 ± 7.76 | — | .60 |
No. of diagnoses | 2.33 ± 1.30 | 2.55 ± 1.23 | — | .49 |
Diagnoses, % (N) | ||||
BP I | 92.30 (36) | — | — | — |
BP II | 7.70 (3) | — | — | — |
ADHD | 46.20 (18) | 77.40 (24) | — | .02 |
ODD | 23.10 (9) | 74.20 (23) | — | .001 |
Any anxiety | 35.90 (14) | 45.20 (14) | — | .59 |
GAD | 15.40 (6) | 29.00 (9) | — | .28 |
Separation anxiety | 15.40 (6) | 25.80 (8) | — | .43 |
Social phobia | 20.50 (8) | 9.70 (3) | — | .37 |
MDD | — | 9.70 (3) | — | — |
No. of medications when medicated | 2.88 ± 1.16 | 2.29 ± 1.14 | .12 | |
Medications | 82.10 (32) | 45.20 (14) | — | .003 |
Antiepileptics | 64.10 (25) | 19.40 (6) | — | .001 |
Atypical antipsychotics | 51.30 (20) | 16.10 (5) | — | .005 |
Lithium | 35.90 (14) | 22.60 (7) | — | .35 |
Stimulants | 35.90 (14) | 29.00 (9) | — | .73 |
Antidepressants | 23.10 (9) | 12.90 (4) | — | .44 |
Mood rating scores | ||||
CDRS | 30.05 ± 9.09 | 26.45 ± 5.24 | — | .06 |
YMRS | 10.84 ± 6.73 | 9.83 ± 7.25 | — | .56 |
MASC t score | 43.63 ± 11.35 | 44.75 ± 10.41 | — | .77 |
Social function scores | ||||
SRS | 80.39 ± 17.30 | 83.27 ± 25.32 | — | .94 |
LIFE: family | 2.70 ± 0.77 | 2.71 ± 0.87 | — | .96 |
LIFE: friends | 3.03 ± 1.12 | 2.72 ± 1.02 | — | .35 |
Note: NP-BD, narrow phenotype bipolar disorder; SMD, severe mood dysregulation; CGAS, Children’s Global Assessment Scale; BP, bipolar disorder; ADHD, attention-deficit/hyperactivity disorder; GAD, generalized anxiety disorder; MDD, major depressive disorder; ODD, oppositional defiant disorder; CDRS, Children’s Depression Rating Scale; YMRS, Young Mania Rating Scale; MASC, Manifest Anxiety Scale for Children; SRS, Social Reciprocity Scale; LIFE, Longitudinal Interval Follow-up Evaluation. All diagnoses are current.