Table 2. Mean and s.d. of Mcm2, Ki67 and geminin LIs and median with percentiles in the Mcm2/Ki67 and geminin/Ki67 ratios in OEDs that progressed to carcinoma and in OEDs with no malignant progression.

Labelling index mean (s.d.)					Median (25–75%)
	Mcm2	Ki67	Geminin	Stat. GLM	Mcm2/Ki67 ratio	Geminin/Ki67 ratio
OED no progr. (n=40)	70.74 (12.84)	45.23 (11.17)	23.71 (7.0)	P<0.001	1.63 (1.28–1.86)	0.51 (0.44–0.58)
OED progr. (n=41)	76.28 (10.90)	43.90 (11.17)	25.06 (7.5)	P<0.001	1.81 (1.52–2.03)	0.58 (0.48–0.68)
t-test	P=0.04	NS	NS		P▪=0.04	P▪=0.02

Abbreviations: GLM=general linear model; OED no prog.=oral epithelial dysplasias with no history of malignant progression; OED prog.=oral epithelial dysplasias that progressed to oral squamous-cell carcinoma; NS=not significant; P▪=Mann–Whitney test.