Table 1. Patient demographic characteristics by diagnosis.
Characteristic | ALL | AML |
---|---|---|
Age in years, median (range) | 5.2 (0.0, 15.1) | 5.5 (0.2, 15.7) |
Male, N (%) | 263 (56) | 40 (51) |
Initial WBC (109l−1) median (IQR) | 11.5 (4.5, 36.3) | 15.8 (6.7, 56.6) |
Initial haemoglobin (g l−1), median (IQR) | 69 (51, 90) | 77 (50, 97) |
Immunophenotype, no (%) | ||
B lineage | 421 (92) | |
T lineage | 35 (8) | |
FAB classification, N (%) | ||
M0 | 7 (9) | |
M1 | 18 (24) | |
M2 | 26 (34) | |
M4 | 8 (11) | |
M5 | 6 (8) | |
M6 | 2 (3) | |
M7 | 7 (9) | |
Risk group, N (%) | ||
Higher risk | 194 (44) | |
Standard riska | 250 (56) | |
Parental education, N (%) | ||
Illiterate | 17 (4) | 3 (4) |
Primary | 290 (63) | 51 (67) |
Secondary | 107 (23) | 18 (24) |
Advanced | 41 (9) | 3 (4) |
Unknown | 4 (1) | 1 (1) |
Hours to travel to clinic, median (IQR) | 2.0 (1.0, 3.0) | 2.0 (1.0, 3.0) |
Monthly household income (dollars), median (IQR) | 150 (100, 250) | 150 (57, 228) |
Body mass index percentile, median (IQR) | 43.2 (11.1, 81.3) | 41.2 (10.7, 77.8) |
Triceps skin-fold thickness percentile, median (IQR) | 17.5 (2.5, 62.5) | 37.5 (17.5, 62.5) |
Mid-upper arm circumference percentile, median (IQR) | 17.5 (2.5, 37.5) | 17.5 (2.5, 37.5) |
Abbreviations: ALL=acute lymphoblastic leukaemia; AML=acute myeloid leukaemia; FAB=French-American-British; IQR=interquartile range; N, number; WBC, white blood cell count; .
Standard risk was defined as DNA index ⩾1.16, WBC <50 × 109/l, age >12 months and <10 years, without any of the following: (1) T-cell lineage, (2) CNS leukaemia at diagnosis, (3) testicular leukaemia or (4) bone marrow M3 on day 15 or M2-M3 on day 36.