Table 1.

EC₅₀ values of the GABA-induced currents of the 18 mutants in loop F of the ρ1 GABA receptor expressed in Xenopus oocytes

Constructs	EC50 (μm)	Constructs	EC50 (μm)
WT	0.81 ± 0.04‡
K210C	1.40 ± 0.09	D219C	3.02 ± 0.25†
K211C	0.93 ± 0.11	E220C	1.46 ± 0.11†
G212C	1.39 ± 0.04	R221C	0.51 ± 0.02†
N213C	4.21 ± 0.29	I222C	0.5 ± 0.03†
D214C	1.75 ± 0.13	S223C	0.66 ± 0.01†
S215C	20.34 ± 1.71	L224C	3.38 ± 0.36†
L216C	0.60 ± 0.03†	S225C	0.53 ± 0.02†
K217C	0.75 ± 0.06†	Q226C	17.60 ± 3.58†
T218C	1.03 ± 0.04†	F227C	0.38 ± 0.32†

^†Values from a previous publication (Sedelnikova et al. 2005).

^‡Value from another publication (Chang & Weiss, 1999b). WT: wild-type ρ1 GABA receptor.