Table 3.
Renal function in 6-month-old-offspring of control or subtotally nephrectomised (STNx) ewes on a low salt diet
| Males | Females | |||
|---|---|---|---|---|
| Control | STNx | Control | STNx | |
| GFR (ml min−1 kg−1) | 4.4 ± 0.7 | 4.4 ± 0.7 | 5.6 ± 0.3 | 5.1 ± 0.4 |
| ERPF (ml min−1 kg−1) | 13.7 ± 1.9 | 18.8 ± 1.9 | 22.4 ± 1.4 | 21.7 ± 1.2 |
| Urine flow rate (ml min−1 kg−1) | 0.09 ± 0.02 | 0.09 ± 0.04 | 0.03 ± 0.00 | 0.03 ± 0.00 |
| Urinary osmolality (mosmol (kg H2O)−1) | 912 ± 191 | 873 ± 213 | 1479 ± 116 | 1282 ± 82 |
| ENa (μmol min−1 kg−1) | 7.3 ± 1.8 | 4.7 ± 2.3 | 3.4 ± 0.7 | 2.4 ± 0.7 |
| EK (μmol min−1 kg−1) | 11.0 ± 1.1 | 10.1 ± 2.5 | 10.6 ± 1.0 | 11.0 ± 1.3 |
| EProtein (μg min−1 kg−1) | 415 ± 37 | 490 ± 90 | 466 ± 49 | 522 ± 56 |
| Na/K ratio | 0.67 ± 0.18 | 0.36 ± 0.16 | 0.35 ± 0.08 | 0.18 ± 0.03 |
Values are means ±s.e.m. GFR, glomerular filtration rate; ERPF, effective renal plasma flow; Ex, excretion of x. Males: control n= 9, STNx n= 6; females: control n= 10; STNx n= 12.