Table 2.
Features of whole-cell current responses evoked by 1 mm ACh in VTA DAergic neuronal classes
| τ (ms) | |||||||
|---|---|---|---|---|---|---|---|
| Type | n | Age (days) | Rt (ms) | Peak (pA) | Steady state (pA) | Fast | Slow |
| ID | 32 | 17 ± 1 | 64 ± 8 | 75 ± 8 | 22 ± 3 | 700 ± 162 (n= 9) | 4040 ± 1833 (n= 9) |
| IID | 11 | 16 ± 1 | 41 ± 7 | 107 ± 19 | 13 ± 5 | 56 ± 8 (n= 23)** | 200 ± 46 (n= 23)** |
| IIID | 8 | 16 ± 1 | 101 ± 22# | 658 ± 154**## | 283 ± 85**## | 505 ± 87 | |
Whole-cell current responses of acutely dissociated VTA DAergic neurons segregated into three classes, types ID, IID and IIID as described in the text, were analysed (numbers of neurons tested, n; age of animals used to isolate neurons, age) to yield mean ±s.e.m. for the parameters indicated (Rt, rising time: time to peak current, ms; peak: peak current amplitude, pA; steady-state: steady-state current amplitude, pA; τ: e-fold current decay time, ms).
**
P < 0.01 compared to ID.
#
P < 0.05 compared between IID and IIID;
##
P < 0.01 compared between IID and IIID.