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. 2008 Dec 1;587(Pt 2):461–475. doi: 10.1113/jphysiol.2008.161760

Figure 4. Effects of antagonism of glutamate receptors in the CVLM on the sympathetic responses to hypoxia and cyanide.

Figure 4

A, inhalation of hypoxic air or injection of CN increased SNA before and after bilateral microinjection of kynurenate into the CVLM. Kynurenate significantly increased SNA and AP (Table 2). Bars under traces of AP = 60 s exposure to hypoxia. B, at baseline, respiratory-related bursts in SNA are present in the sympathetic response to hypoxia. C, after kynurenate, hypoxia-induced oscillations in SNA are absent. The magnitude of the sympathetic response to hypoxia (D) or CN (E) was significantly larger after antagonism of glutamate receptors in the CVLM. *Significant difference from control values.