Table 2.
Phenylephrine induced baroreflex responses
Pressor response (%SI mmHg−1) |
Sympathetic gain (mmHg) |
|||
---|---|---|---|---|
WKY | SHR | WKY | SHR | |
Neonates | 19.7 ± 2.9 | 28.6 ± 5.8 | 4.3 ± 1.3 | 5.8 ± 2.8 |
3 weeks | 18.2 ± 2.2 | 20.9 ± 3.8 | 2.8 ± 0.7 | 3.8 ± 0.8 |
5 weeks | 39.4 ± 9.4# | 28.3 ± 1.8 | 2.2 ± 0.6 | 1.6 ± 0.1# |
Mean (±s.e.m.) pressor response and degree of baroreflex evoked sympathoinhibition (sympathetic gain) in response to phenylephrine (10 μg, i.a.). #P < 0.05 compared to both neonate and 3-week-old of same strain (Student's t test), n= 5 per group.