Table 3.
Peripheral chemoreflex responses
| Δ respiratory rate (%) |
Sympathoexcitation (%) |
Pressor (mmHg) |
||||
|---|---|---|---|---|---|---|
| WKY | SHR | WKY | SHR | WKY | SHR | |
| Neonates | 44.8 ± 12 | 79.2 ± 24 | 45.6 ± 10 | 38.5 ± 4 | 3.7 ± 0.8 | 8.2 ± 1.6* |
| 3 weeks | 43.8 ± 8 | 52.9 ± 14 | 26.8 ± 5 | 48.6 ± 10 | 5.6 ± 0.9 | 10.8 ± 2.7 |
| 5 weeks | 36.7 ± 11 | 66.4 ± 16 | 49.3 ± 19 | 36.5 ± 5 | 8.0 ± 1.4 | 6.6 ± 2.5 |
Change in respiratory rate, activation of tSNA and pressor response following stimulation of peripheral chemoreceptors with sodium cyanide (mean ±s.e.m.).
*
P < 0.05 compared to WKY of same age, Student's t test, n= 5 per group.