Table 1.
Basal measurements
| Study 1 | Study 2 | ||||
|---|---|---|---|---|---|
| C1 | PI50 | C2 | PI40 | L | |
| Maternal | |||||
| Glucose (mmol l−1) | 3.76 ± 0.11 | 3.44 ± 0.20 | 3.42 ± 0.13 | 3.58 ± 0.20 | 3.22 ± 0.13 |
| Lactate (mmol l−1) | 0.60 ± 0.1 | 0.32 ± 0.05 | 0.55 ± 0.08 | 0.65 ± 0.07 | 0.47 ± 0.06 |
| Insulin (μg l−1) | 1.5 ± 0.3 | 0.8 ± 0.1 | 1.1 ± 0.2 | 1.4 ± 0.4 | 0.6 ± 0.1 |
| Cortisol (μg dl−1) | 1.8 ± 0.4 | 1.5 ± 0.3 | 0.9 ± 0.2 | 1.3 ± 0.2 | 0.9 ± 0.1 |
| ACTH (pg ml−1) | 16 ± 2 | 13 ± 1 | 22 ± 5 | 39 ± 21 | 17 ± 3 |
| Adrenaline (pg ml−1) | 10 ± 1 | 17 ± 3 | 24 ± 5 | 29 ± 5 | 19 ± 4 |
| Noradrenaline (pg ml−1) | 115 ± 15 | 140 ± 12 | 482 ± 140 | 511 ± 150 | 312 ± 84 |
| Fetal | |||||
| Glucose (mmol l−1) | 0.84 ± 0.06 | 0.81 ± 0.06 | 0.82 ± 0.04 | 0.81 ± 0.03 | 0.73 ± 0.03 |
| Lactate (mmol l−1) | 0.92 ± 0.06 | 0.90 ± 0.06 | 0.94 ± 0.05 | 1.02 ± 0.09 | 1.13 ± 0.11 |
 (mmHg) |
19.6 ± 0.7 | 18.4 ± 0.9 | 20.2 ± 0.7 | 18.6 ± 1.3 | 17.7 ± 0.8 |
| pH | 7.34 ± 0.00 | 7.34 ± 0.01 | 7.35 ± 0.01 | 7.34 ± 0.01 | 7.34 ± 0.01 |
| K+ (mmol l−1) | 2.7 ± 0.1 | 2.6 ± 0.3 | 2.8 ± 0.1 | 3.1 ± 0.2 | 2.9 ± 0.1 |
| MAP (mmHg) | 43 ± 1 | 43 ± 1 | 43 ± 1 | 45 ± 2 | 42 ± 2 |
| Heart rate (BPM) | 173 ± 6 | 174 ± 5 | 168 ± 4 | 183 ± 3† | 169 ± 3 |
| FA flow (ml min−1) | 39 ± 6 | 33 ± 5 | 32 ± 4 | 37 ± 4 | 36 ± 6 |
| CA flow (ml min−1) | 83 ± 12 | 77 ± 8 | 81 ± 5 | 89 ± 10 | 79 ± 11 |
| FVR (mmHg min ml−1) | 1.44 ± 0.30 | 1.92 ± 0.58 | 1.35 ± 0.11 | 1.49 ± 0.32 | 1.09 ± 0.12 |
| CVR (mmHg min ml−1) | 0.91 ± 0.36 | 0.62 ± 0.06 | 0.60 ± 0.05 | 0.57 ± 0.06 | 0.53 ± 0.04 |
Values are mean ±s.e.m. C1, n= 10; PI50, n= 9; C2, n= 10; PI40, n= 9; L, n= 6. MAP, mean arterial pressure; FA, femoral artery; CA, carotid artery; FVR, femoral vascular resistance; CVR, carotid vascular resistance. †P < 0.01 versus C2.