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. 2008 Dec 15;587(Pt 3):625–640. doi: 10.1113/jphysiol.2008.165217

Figure 4. Pharmacological characterization of Kv currents.

Figure 4

A, total Kv current density versus voltage curves were obtained after blockade of BKCa current with 500 nm paxilline in BPN (•) and BPH (^) VSMCs; n= 22 cells in each group, *P < 0.05. Representative examples of the protocol for pharmacological dissection of the Kv currents are shown for one BPN (B) and one BPH (C) cell. The graphs show the I–V relationships in the presence of 500 nm paxilline (total Kv current), after application of 5 μm correolide, and in the presence of two TEA concentrations. The contribution of each component (Kv1–Kv4) is represented by the shaded areas. Traces show the currents obtained upon depolarization to +40 mV with each of the blockers.