Figure 6. Myostatin mRNA, LAP and mature protein in gastrocnemius muscles of male and female wild-type (C57) and Stat5b^−/− mice at 20 weeks of age.

Values are mean (±s.e.m.) (n= 6 per group). Unlike letters indicate a significant difference among groups (^a,bP < 0.001). A representative Western blot is shown for myostatin LAP and mature protein for each sex and genotype. The abundance of actin was assessed to demonstrate the similarity in loading of protein per lane.