Table 4.
Plasma hormone concentrations from postnatal days 7–35 in response to weaning diets high in fibre or protein
| Age (days) | |||||
|---|---|---|---|---|---|
| 7 | 14 | 21 | 28 (on diet) | 35 (on diet) | |
| GLP-1 (pm) | |||||
| Control | 139.5 ± 23.0† | 87.1 ± 18.12 | 43.34 ± 4.90 | 24.0 ± 0.74 | 26.6 ± 2.6 |
| High fibre | 37.4 ± 2.19** | 38.9 ± 3.22** | |||
| High protein | 26.8 ± 2.05 | 27.6 ± 1.78 | |||
| Leptin (pm) | |||||
| Control | 292.9 ± 44.0 | 397.5 ± 39.1 | 376.2 ± 45.3 | 346.8 ± 51.3 | 321.8 ± 48.9 |
| High fibre | 208.4 ± 25.0* | 216.7 ± 20.6* | |||
| High protein | 273.2 ± 30.5 | 269.5 ± 32.1 | |||
| Insulin (pm) | |||||
| Control | 232.7 ± 46.2 | 163.9 ± 21.5 | 237.9 ± 73.1 | 175.8 ± 45.6 | 215.5 ± 38.3 |
| High fibre | 123.5 ± 17.5 | 154.4 ± 40.5 | |||
| High protein | 111.4 ± 11.5 | 188.0 ± 23.4 | |||
| Glucagon (pm) | |||||
| Control | 178.6 ± 42.0 | 222.1 ± 43.2 | 234.0 ± 45.5 | 118.7 ± 22.6 | 175.2 ± 36.7 |
| High fibre | 156.6 ± 31.9 | 160.7 ± 17.6 | |||
| High protein | 159.1 ± 40.9 | 192.5 ± 35.9 | |||
| Amylin (pm) | |||||
| Control | 11.8 ± 0.3 | 11.6 ± 0.6 | 12.9 ± 1.4 | 12.5 ± 0.6 | 15.2 ± 1.2 |
| High fibre | 17.3 ± 2.8 | 15.9 ± 3.2 | |||
| High protein | 11.8 ± 0.2 | 12.7 ± 0.7 | |||
Values are means ±s.e.m. with an n= 11 males (M) and 5 females (F) on day 7; n= 8 (M) and 8 (F) on day 14; n= 7 (M) and 9 (F) on day 21; n= 6 (M) and 6 (F) per diet group on days 28 and 35. No sex differences were found for plasma hormones and therefore sexes were combined. *Significant difference between high fibre versus control (P < 0.01) in both sexes at d28 and d35. **Significant difference between high fibre versus control and high protein diets (P < 0.001) in both sexes at d28 and d35. †Significant age difference, independent of diet where day 7 is different from days 21, 28 and 35; and day 14 is different from days 28 and 35 (P < 0.05).