FIGURE 2.

GLEPP1 expression in human and murine leukocytes. Expression of mRNA encoding the GLEPP1 catalytic domain was measured by qPCR, as a percentage of GAPDH mRNA, starting with RNA from human (A) or mouse (B) cells. Human cells for RNA isolation were from two or more donors; mouse cells were from the indicated strains. BMDMs were either from PI3Kγ knock-out (KO) (40) or wild type (wt) mice, as indicated. C and D, Glepp1 mRNA expression in variously activated human peripheral blood mononuclear cells, T cells, and dendritic cells. MLR, mixed lymphocyte reaction.