Fig. 4.

Following the processing stream outlined in Fig. 2, BOLD data was projected through the simulated optical sensitivity (forward) matrices to produce predicted spatiotemporal profiles of the response across the optical probe. Shown above, correspondence was seen between the response predicted from the BOLD-fMRI data and the measured optical HbR response. The DOI and BOLD time courses above have been normalized to the single maximum response to allow comparisons of the amplitudes across the probe. The HbR time courses have been inverted for this comparison.