Table 3.

Results of genetic screening for BRCA1/2 mutations

Result	Interpretation
Positive for deleterious mutation	Individual has high risk of breast and ovarian cancer
Negative for a mutation	Result interpreted with caution especially in the setting of a strong family history
Mutation of unknown significance	Mutation has not been definitively shown to be deleterious either because it is rare or because it may not completely track with the family history of the individual
Mutation favoring benign polymorphism	Although not certain these mutations seem to not be associated with a high risk for breast and ovarian cancer