Table 1.
Characteristics of Patients with Major Depression (remitters and non-remitters) and Healthy Volunteers.
| Remitters N (%) | Non-Remitters N (%) | Controls N (%) | Remitters vs. Non-remitters (t-test or fisher’s P-value) | Non-remitters vs. Controls (t- test or fisher’s P-value) | Remitters vs. Controls (t-test or fisher’s P-value) | |
|---|---|---|---|---|---|---|
| Total N | 7 | 12 | 41 | |||
| Female | 5 (71.4) | 10 (83.3) | 20 (48.8) | .60 | .05 | .42 |
| Prior Meds | 5 (71.4) | 8 (66.7) | 0 (0) | 1 | <.00001 | <.0001 |
| Age | 38.9 ± 11.4 | 41.7 ± 15.1 | 39.0 ± 16.1 | .68 | .60 | 1.00 |
| # of prior suicide attempters | 3 (42.9) | 5 (41.7) | 0 (0) | 1 | .0003 | .0020 |
| HAMD1 24 Baseline | 25.0 ± 8.5 | 25.7 ± 7.9 | 0.61 ± 0.89 | .86 | <.0001 | <.0001 |
| HAMD1 24 1 year | 4.1 ± 3.4 | 23.8 ± 8.8 | n/a | <.0001 | n/a | n/a |
| Family hx of MDD | 1 (14.3) | 9 (75) | 0 | .02 | .15 | |
| # of 1st degree relatives w/MDD | 0.14 ± 0.38 | 1.33 ± 1.07 | 0 ± 0 | .012 | <.00001 | .013 |
| Ethnicity | .38 | .16 | .82 | |||
| Asian | 1 (14.3) | 1 (8.3) | 6 (14.6) | |||
| Black | 2 (28.6) | 0 (0) | 6 (14.6) | |||
| Hispanic | 1 (14.3) | 4 (33.3) | 6 (14.6) | |||
| White | 3 (42.9) | 6 (50) | 23 (56.1) | 12 | .752 | .692 |
| >1 Race | 0 (0) | 1 (8.3) | 0 (0) | |||
| Comorbid Axis I | 3 (42.9) | 6 (50) | 0 | 1 | <.0001 | .0020 |
| Comorbid Panic Disorder | 1 (14.3) | 3 (25) | 0 | 1 | .0094 | .15 |
| Injected dose (mCi) | 15.10 ± 2.17 | 13.48 ± 4.55 | 11.97 ± 4.12 | .39 | .28 | .06 |
| Injected mass(μg) | 4.33 ± 1.15 | 4.09 ± 1.38 | 4.50 ± 1.47 | .24 | .89 | .78 |
1
Hamilton Depression Rating Scale
2
comparing to all other groups pooled given low sample size.