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A serial dilution of mouse joint DNA is detectable by Nidogen molecular beacons. Amplification plots of five-fold dilution of mouse DNA used in PCR assays with Nidogen molecular beacon for detection of nidogen amplification products are shown (A). A standard curve (B) and high coefficient of correlation (r2 = 0.998) indicates that the Nidogen molecular beacon is effective in detecting 200 ng to the low level (1 ng) of mouse DNA.
