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Kinetic data for selected 14B7 and M18 variants
| Mutant | kon (M−1 s−1) | koff (s−1) | KD (M) |
|---|---|---|---|
| 14B7 | 1.5 × 106 | 3.9 × 10−3 | 2.6 × 10−9 |
| 14B7-L46F | 1.2 × 106 | 4.0 × 10−4 | 3.2 × 10−10 |
| M18-F46L | 5.5 × 105 | 3.2 × 10−4 | 5.8 × 10−10 |
| M18 | 1.6 × 106 | 4.8 × 10−5 | 2.9 × 10−11 |
