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Secondary steady-state pharmacokinetic parameters of unconjugated rotigotine in plasma after rotigotine patch application with or without domperidone comedication (n = 16)
| Parameter | With domperidone | Without domperidone |
|---|---|---|
| Cmin,ss (pg ml−1) | 144 (53) | 138 (54) |
| Cave,ss (pg ml−1) | 214 (61) | 221 (56) |
| AUC(0–tz) (pg h−1 ml−1) | 6487 (58) | 6632 (55) |
Data are presented as geometric mean and geometric coefficient of variation (%).
