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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Semin Arthritis Rheum. 2008 Jan 25;38(1):41–54. doi: 10.1016/j.semarthrit.2007.09.005

Table 3.

Regression coefficients for log-transformed hsCRP levels* by clinical features and autoantibodies

Unadjusted Adjusted
Model 1† Model 2‡ Model 3§
Variables β 95% CI P B 95% CI P % Red β 95% CI P % Red β 95% CI P % Red
Clinical features
  Fever 0.08 −0.01, 0.18 0.094 0.03 −0.06, 0.12 NS 61 0.05 −0.04, 0.14 NS 36.3 0.04 −0.06, 0.14 NS 46
  Discoid rash 0.14 0.03, 0.26 0.015 0.03 −0.08, 0.14 NS 80 0.01 −0.10, 0.13 NS 90.8 0.04 −0.08, 0.15 NS 75
  Raynaud phenomenon −0.09 −0.18, 0.00 0.053 −0.02 −0.11, 0.06 NS 73 −0.04 −0.13, 0.06 NS 60.7 −0.04 −0.13, 0.06 NS 61
  Livedo reticularis −0.13 −0.24, −0.03 0.013 −0.05 −0.15, 0.06 NS 65 −0.08 −0.19, 0.04 NS 43.6 −0.07 −0.19, 0.04 NS 44
  Pericarditis 0.13 0.02, 0.23 0.023 0.09 −0.01, 0.19 0.071 27 0.04 −0.06, 0.15 NS 64.8 0.05 −0.06, 0.16 NS 60
  Myocarditis 0.41 0.08, 0.73 0.014 0.39 0.10, 0.68 0.009 3 0.44 0.13, 0.76 0.006 −9.1 0.57 0.22, 0.92 0.002 −39
  Murmur 0.21 0.12, 0.29 <0.001 0.11 0.02, 0.20 0.019 47 0.15 0.05, 0.25 0.003 27.3 0.16 0.06, 0.26 0.002 22
  Pleuritis 0.10 0.01, 0.19 0.036 0.09 0.01, 0.18 0.032 6 0.10 0.01, 0.19 0.031 −2.1 0.08 −0.01, 0.18 0.094 17
  Interstitial pulmonary fibrosis 0.25 0.08, 0.41 0.003 0.18 0.03, 0.33 0.019 27 0.16 −0.00, 0.32 0.051 35.9 0.17 0.01, 0.33 0.043 31
  Pulmonary hypertension 0.24 0.08, 0.41 0.003 0.10 −0.05, 0.25 NS 59 0.15 −0.01, 0.31 0.066 38.7 0.18 0.01, 0.34 0.036 27
  Colitis, vasculitis, and serositis 0.24 0.05, 0.44 0.013 0.21 0.03, 0.38 0.021 16 0.26 0.06, 0.46 0.012 −5.3 0.28 0.07, 0.49 0.008 −15
  Seizure 0.21 0.04, 0.39 0.019 0.23 0.07, 0.39 0.006 −7 0.19 0.02, 0.36 0.027 9.9 0.17 −0.01, 0.35 0.069 22
  Anemia 0.14 0.05, 0.23 0.003 0.07 −0.02, 0.16 NS 48 0.09 −0.00, 0.19 0.055 32.8 0.12 0.02, 0.22 0.021 14
Autoantibodies
  Anti-dsDNA 0.00 0.00, 0.00 <0.001 0.00 0.00, 0.00 <0.001 0 0.00 0.00, 0.00 <0.001 0 0.00 0.00, 0.00 <0.001 0
  Lupus anticoagulant 0.18 0.08, 0.28 <0.001 0.13 0.04, 0.22 0.007 28 0.14 0.04, 0.24 0.006 22.8 0.13 0.03, 0.24 0.013 26

Abbreviations:β, regression coefficient; CI, confidence interval; NS, not significant.

*

Log-transformed values of hsCRP ranged from −1.00 to 1.93.

†

Model 1: Adjusted for age, gender, ethnicity, disease duration, body mass index, and education

‡

Model 2: Adjusted for age, gender, ethnicity, disease duration, body mass index, education, and SELENA-SLEDAI.

§

Model 3: Adjusted for age, gender, ethnicity, disease duration, body mass index, education, SELENA-SLEDAI, current prednisone dose, statin use, and estrogen use.

Percentage reduction in regression coefficients from the unadjusted model, calculated as: (regression coefficientunadjusted − regression coefficientmodel 1 or 2 or 3)/(regression coefficientunadjusted).