Table 2.
Clinical characteristics of the stomach cancer cases entered in the population-based cancer registry of Valdivia 1998-2002 (n = 529)
| Characteristic | Cases | Total (%) | Males (%) | Females (%) | P-value sex diff. |
| Sign and symptoms at diagnosis | |||||
| Weight loss | 294 | 55.6 | 61.1 | 43.3 | < 0.001 |
| Epigastric pain | 285 | 53.9 | 57.0 | 47.0 | 0.03 |
| Gastrointestinal bleeding | 108 | 20.4 | 21.4 | 18.3 | 0.42 |
| Vomiting | 106 | 20.0 | 20.8 | 18.3 | 0.50 |
| Abdominal distension | 83 | 15.7 | 14.8 | 17.7 | 0.40 |
| Palpable epigastric mass | 56 | 14.7 | 12.9 | 19.2 | 0.016 |
| Ascites | 51 | 13.4 | 13.3 | 13.5 | 0.97 |
| Supraclavicular adenopathy | 31 | 8.5 | 9.7 | 5.1 | 0.16 |
| Main detection source | |||||
| Histological studies1 | 404 | 76.4 | 81.3 | 65.2 | < 0.001 |
| Radiological diagnosis | 25 | 4.7 | 4.9 | 4.3 | 0.74 |
| Clinical or autopsy | 39 | 7.3 | 7.2 | 7.9 | 0.75 |
| Only death certificate | 61 | 11.5 | 6.6 | 22.6 | < 0.001 |
| Duration of symptoms2 | |||||
| < 3 mo | 126 | 32.9 | 35.9 | 24.2 | 0.033 |
| 3 to 6 mo | 98 | 25.6 | 25.4 | 26.3 | 0.86 |
| > 6 mo | 159 | 41.5 | 38.7 | 49.5 | 0.06 |
| Main diagnostic workout | |||||
| Gastric endoscopy | 412 | 79.4 | 84.6 | 67.7 | < 0.001 |
| Gastric biopsy | 401 | 75.8 | 80.8 | 64.6 | < 0.001 |
| Ecography | 191 | 36.1 | 37.8 | 32.3 | 0.22 |
| Computed tomography | 114 | 21.6 | 22.7 | 18.9 | < 0.001 |
| Staging TNM | |||||
| Stage I | 9 | 1.7 | 2.2 | 0.6 | 0.19 |
| Stage II | 20 | 3.8 | 2.5 | 6.7 | 0.02 |
| Stage III | 53 | 10.0 | 10.4 | 9.1 | 0.65 |
| Stage IV | 297 | 56.1 | 58.6 | 50.6 | 0.09 |
| Not determined | 150 | 28.4 | 26.3 | 32.9 | 0.12 |
| Histological type | |||||
| Tubular adenocarcinoma | 148 | 36.0 | 35.2 | 38.3 | 0.56 |
| Tubulopapillary adenocarcinoma | 35 | 8.5 | 7.6 | 11.2 | 0.25 |
| Papillary adenocarcinoma | 11 | 2.7 | 2.0 | 4.7 | 0.14 |
| Mucinous adenocarcinoma | 11 | 2.7 | 2.3 | 3.7 | 0.43 |
| Undefined adenocarcinoma | 83 | 20.2 | 22.4 | 14.0 | 0.06 |
| Signet ring cell carcinoma | 77 | 18.7 | 18.1 | 20.6 | 0.57 |
| Non Hodgkin lymphoma | 6 | 1.5 | 1.6 | 0.9 | 0.60 |
| Neuroendocrine carcinoma | 4 | 1.0 | 0.7 | 1.9 | 0.27 |
| Other carcinoma | 36 | 8.8 | 9.5 | 6.5 | 0.35 |
| Tumor location | |||||
| Body | 57 | 10.8 | 11.5 | 9.1 | 0.42 |
| Fundus | 158 | 29.9 | 33.7 | 21.3 | 0.004 |
| Antrum | 122 | 23.1 | 21.9 | 25.6 | 0.35 |
| All stomach | 33 | 6.2 | 6.8 | 4.9 | 0.39 |
| Unknown | 159 | 30.1 | 26.0 | 39.0 | 0.003 |
| Habits | |||||
| Tobacco use | 346 | 44.8 | 51.4 | 29.1 | < 0.001 |
| Alcohol use | 338 | 61.2 | 73.6 | 31.3 | < 0.001 |
Includes 3 cases diagnosed based on a biopsy of metastasis;
Time between first symptoms and diagnosis.