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CpG-B alone induces secretion of Ig from CD27+ B cells. CD27+ B cells of 12 HIV-negative (HN), 12 HIV-viremic (V), and 12 HIV-aviremic (AV) individuals were cultured without stimulation (A) or with CpG-B (2.5 μg/ml) (B). Culture supernatants were collected at day 3 and assayed for total IgM, IgA, and IgG. Black horizontal lines indicate median counts.
