Skip to main content
. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Glia. 2009 Jun;57(8):850–859. doi: 10.1002/glia.20811

Figure 5. SCs in the mutant sciatic nerves develop into pre/promyelinating or myelinating SCs but not into non-myelinating SCs.

Figure 5

Transverse sections (A and B) and an adjacent section (C) of control sciatic nerves at P15 were stained for N-CAM (green, A), neurofilament (blue, A), Oct-6 (red, B), or Krox-20 (red, C) to detect pre/promyelinating, myelinating, and non-myelinating SCs. Adjacent transverse sections (D and E, F and G, and H) of mutant sciatic nerves at P15 were stained for N-CAM (green, D and F), neurofilament (blue, D-G), Oct-6 (red, E), Krox-20 (red, G and H) and laminin γ1 to detect pre/promyelinating, myelinating, and non-myelinating SCs and laminin expression. In mutant sciatic nerves, only pre/promyelinating.or myelinating SCs are present but no non-myelinating SCs are detected. Arrows: background staining of connective tissue (epineurium). Bar: 25 μm.