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. 1999 Mar 2;96(5):1881–1885. doi: 10.1073/pnas.96.5.1881

Figure 3.

Figure 3

The ΔK12H4.8 homologue contains an RNase III motif. Amino acids 422–511 of the ΔK12H4.8 homologue were aligned with the hypothetical helicase K12H4.8 in C. elegans (P34529) and with two bacterial RNases III by using the clustal w program (European Bioinformatics Institute). The RNase III signature [DEQ] - [RQ] - [LM] - E - [FYW] - [LV] - G - D - [SAR], present in the four proteins, is shown in bold. The four proteins share 24% (22/93) identity and 57% (53/93) similarity over 93 aa centered around the RNase III motif. Amino acid identity and conservative differences between the proteins are indicated by ∗ and . or :, respectively.