Table V.
Indices of oxidative stress (with standard deviations) in the ileum mucosa in mice challenged with S. Typhimurium and treated with ofloxacin and/or the probiotic L. fermentum ME-3.
| Experimental groups | LPO (pmol/mg protein) | GSSG/GSH |
|---|---|---|
| Salmonella Typhimurium challenged mice (Gr1) | 338±461;4 | 0.26±0.413;5 |
| ST treated with ofloxacin (OFX) (Gr2) | 228±412 | 0.26±0.11 |
| ST treated with strain ME-3 (Gr3) | 169±111;2 | 0.16±0.203 |
| ST treated with OFX + strain ME-3 (Gr4) | 161±271;2 | 0.17±0.113 |
| Control (PBS) | 157±244 | 0.11±0.25 |
GSSG/GSH, glutathione redox ratio; LPO, lipid peroxides; OFX, ofloxacin; PBS, phosphate-buffered saline; ST, Salmonella Typhimurium.
p < 0.001 Gr1 vs Gr3 and Gr4;
p = 0.002 Gr2 vs Gr3 and Gr 4;
p = 0.006 Gr1 vs Gr3 and Gr4;
p < 0.001 Gr1 vs control;
p < 0.003 Gr1 vs control.