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. 2009 Apr 29;4(4):e5391. doi: 10.1371/journal.pone.0005391

Figure 2. FX06 decreased capillary leak following LPS injection in rats.

Figure 2

One hour after LPS injection (i.v., 12 mg/kg), FX06 (2.4 mg/kg) or an equal volume of NaCl (100 µl) were injected i.v.; 350 min after LPS injection, FluoSpheres® were injected i.v.; 360 min. after LPS injection, rats were sacrificed. The right lung was used for histology and photographed on a laser scan microscope. Examples of images from LPS (A) or LPS+FX06-treated animals (B). From the entire left lung, FluoSpheres® were recovered and fluorescence measured by ELISA as described in Methods (C). The difference between LPS and LPS plus FX06 was significant (n = 11 per group; * denotes p<0.05, mean+/−SD).