Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Jan 23;329(1):314–323. doi: 10.1124/jpet.108.150136

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2009, The American Society for Pharmacology and Experimental Therapeutics

PMC Copyright notice

Fig. 5. — The FAAH(-/-) antipruritic phenotype is mediated through a CB₁ receptor mechanism of action. FAAH(+/+) and FAAH(-/-) mice on a C57BL/6 background were given an intraperitoneal injection of rimonabant (1 mg/kg) 15 min before compound 48/80. The rimonabant (hatched bars) did not affect scratching behavior in FAAH(+/+) mice compared with 1:1:18 vehicle controls but reversed the phenotypic reduction in FAAH(-/-) mice. ⋆⋆, p < 0.01 versus FAAH(+/+) vehicle group; ##, p < 0.01 versus FAAH(-/-) vehicle group (Tukey's post hoc test). n = 8 mice/group.