Fig. 6.
Mice that only express FAAH in neural tissues do not display a phenotypic reduction in compound 48/80-induced scratching. Heterozygous mice (+/-; white bar), global FAAH knockout mice (-/-; black bar), and conditional knockout mice expressing FAAH isolated to neural tissues (NS; gray bar). FAAH(-/-) mice display typical phenotypic reduction in scratching response (⋆⋆, p < 0.01; Tukey's post hoc test) compared with FAAH(+/-) controls; however, this phenotype is absent in mice with FAAH expression active in neural tissues (##, p < 0.01 versus FAAH(-/-) group). n = 10 mice/group.