Fig. 5.

Time course of phenmetrazine effects on responding maintained by food and cocaine (0.01–0.1 mg/kg/injection). Data obtained during availability of 0.01, 0.032, and 0.1 mg/kg/injection cocaine are shown in the top, middle, and bottom rows of graphs, respectively. Data obtained during saline treatment are shown in the left column, and data obtained during phenmetrazine treatment are shown on the right. Abscissae, consecutive days of treatment. All treatments were implemented for a period of 7 days. The shaded region in the middle right shows cocaine- and food-maintained responding during the 7 days after termination of phenmetrazine treatment (post-treatment days 1–7, P1–P7). Left ordinates, number of injections per day (maximum = 80). Right ordinates, number of food pellets per day (maximum = 100). All points show mean ± S.E.M. in three monkeys.