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13CO2 breath patterns (mean ± S.E.) versus time in all healthy volunteers (n = 25) after oral administration of a solution consisting of 100 mg of [13C]pantoprazole sodium-sesquihydrate and 2.1 g of sodium bicarbonate. Breath samples were collected at baseline (before) and up to 120 min after pantoprazole dosing. The amounts of 13CO2 in breath (expressed as DOB) versus time (A) and the cumulative PDR versus time (B) are presented as mean ± S.E.
