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. 2009 Jan 5;329(1):150–158. doi: 10.1124/jpet.108.145938

Fig. 2.

Fig. 2.

TIQ-A administration promotes an enrichment of SMCs and an increase in collagen content in regressed atherosclerotic plaques. Immunohistochemistry analysis with antibodies to SMA (A) or trichrome staining (B) of plaques from the different experimental groups; quantitation of immunoreactivity or trichrome stain was conducted using Image-Pro Plus software (MediaCybernetics, Inc., Bethesda, MD) and expressed as immunoreactivity per millimeter squared. *, difference from ApoE(-/-) mice fed the high-fat diet for 16 weeks; ‡, difference from ApoE(-/-) mice fed the high-fat diet for 12 weeks followed with 4 weeks of regular diet; P < 0.01.