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. 2009 Jan 5;329(1):150–158. doi: 10.1124/jpet.108.145938

Fig. 5.

Fig. 5.

TIQ-A-induced reduction in the expression of chemokines and adhesion molecules is associated with a modulation of TNF expression. Thoracic aortas isolated from the four experimental groups (n = 6) were collected and subjected to RNA extraction and cDNA generation. cDNA was subjected to real-time PCR with primers specific to murine TNF or β-actin. *, difference from ApoE(-/-) mice fed high-fat diet for 16 weeks; ‡, difference from ApoE(-/-) mice fed the high-fat diet for 12 weeks followed by 4 weeks of the regular diet; †, difference from ApoE(-/-) mice fed the high-fat diet and administered TIQ-A for 4 weeks. P < 0.01.