Table 1.
Treatment | Final Body Weight, g | Weight Gain, g/8 wk | Water Intake,* ml/day | Kidney Weight,† g | Urine 8-Isoprostane, ng/day | Plasma Creatinine, pmol/l | Plasma Aldosterone, nmol/l |
---|---|---|---|---|---|---|---|
NF | 304±12 | 97±4 | 17.8±0.7 | 0.83±0.03 | 6.2±0.9 | 23.5±2.9 | 2.28±0.75 |
HF | 336±14 | 100±10 | 18.6±1.8 | 0.90±0.03 | 15.8±1.3 | 23.5±2.9 | 1.31±0.62 |
P value | 0.11 | 0.81 | 0.67 | 0.11 | <0.001‡ | 1.0 | 0.36 |
Data are means ± SE; n = 5 or 6 rats/treatment. NF, normal fat; HF, high fat.
Average of 2 measurements in metabolic cages;
average right and left;
significantly different (P < 0.05) as determined by unpaired t-test.