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The role of myosin light chain (MLC) kinase in the motogenic effect of strain. A: p38 inhibition (SB203580) did not block MLC phosphorylation in response to strain (n = 4, *P < 0.03), but inhibiting PI3K (LY294002) or AKT (B), GSK (SB415286, C) or ERK (PD98059, D) blocked strain-associated MLC phosphorylation (n ≥ 4, *P < 0.002) in Caco-2 cells.
