Fig. 1.

Concentrations of blood glucose (A), plasma insulin (B), plasma glucagon-like peptide-1 (GLP-1) (C), and plasma glucose-dependent insulinotropic polypeptide (GIP) (D) in response to intragastric infusion of 500 ml solutions containing either 1) 50 g sucrose, 2) normal saline, 3) 80 mg sucralose (0.4 mM), or 4) 800 mg sucralose (4 mM) in 7 healthy subjects. *Sucrose vs. saline, P < 0.05. Data are means ± SE. There were no significant differences in blood glucose, plasma insulin, plasma GLP-1, and plasma GIP between either load of sucralose and saline.