Table 4.

Infarct size measurements and caspase-3 activity

Area at risk, %	Border Zone Over Area at Risk, %	Infarct Zone Over Area at Risk, %	Caspase-3 Activity, pmol AFC·min−1·mg protein−1
			Total Tissue	Perfused Tissue	Area at Risk
48±2	75±17	25±17	2.0±1.2	0.3±0.3	3.9±2.1

Values are means ± SD. Two rats were subjected to a myocardial infarction protocol of 30 min of occlusion and 4 h of reperfusion. Infarct size was calculated using planimetry. Caspase-3 activity at the area of risk was measured as described in materials and methods. Total tissue activity included normally perfused tissue and tissue of area at risk.