Table 1.

Physiological assessment of aortic constriction at baseline and after transaortic constriction reversal by right and left carotid blood flow determination by pulse-Doppler analysis

	Peak Right Carotid Artery Velocity, m/s	Peak Left Carotid Artery Velocity, m/s	Peak Right/Left Carotid Artery Velocity
Prebanding baseline
WT	42.1±6.3	40.8±5.5	1.0±0.5
MuRF1−/−	50.5±6.2	48.1±2.4	1.0±0.4
Postbanding baseline
WT	21.7±9.3	91.0±8.9	4.2±0.6*
MuRF1−/−	25.7±13.7	98.4±6.6	3.8±1.2*
4 days postdebanding
WT	63.9±8.5	31.2±9.6	2.6±0.4†
MuRF1−/−	75.4±7.3	80.6±5.6	1.2±0.5
1 wk postdebanding
WT	57.8±6.8	58.3±3.0	0.9±0.8
MuRF1−/−	67.2±6.6	61.8±5.5	1.1±0.5

Values are means ± SE; n = 3 mice/group. Carotid Doppler velocities were performed at baseline and 4 and 7 days after mice had been debanded. WT, wild type; MuRF1, muscle ring finger-1.

^*P < 0.001 compared with baseline;

^†P < 0.001 compared with postdebanded MuRF1^−/− and baseline WT peak velocities.