Fig. 7.
Effects of activation and blockade of NTS A2a adenosine receptors on baroreflex control of HR. The changes in range, Gmax, and upper and lower plateau of HR baroreflex response functions were evoked by bilateral microinjections into the NTS of A2a adenosine receptor agonist (CGS-21680, 2.0 and 20 pmol in 50 nl), selective A2a adenosine receptor antagonist (ZM-241385, 40 pmol in 100 nl), nonselective A1 + A2a adenosine receptor antagonist (8-SPT, 1 nmol in 100 nl), and respective volume controls (ACF, 50 and 100 nl for the agonist and the antagonists, respectively). *P < 0.05 vs. ACF.