Table 2.

Potency of ACh in thoracic aortas from Gla^+/0 and Gla^−/0 mice in the presence of COX inhibitors with endothelium

	−log EC50, M
	Gla+/0	Gla−/0
Control	7.17±0.05 (8)	7.14±0.06 (10)
Indomethacin	7.24±0.05 (10)	7.12±0.05 (10)
Valeryl salicylate	7.24±0.05 (8)	7.12±0.05 (8)
NS-398	7.13±0.07 (8)	6.63±0.10†‡ (8)

Values are means ± SE for number of animals in parentheses.

^†P < 0.05 vs. Gla^+/0 in respective treatment group (by unpaired t-test).

^‡P < 0.05 vs. Gla^−/0 control (by 1-way ANOVA with Newman-Keuls multiple comparison).