Table 3.

Potency of SNP in thoracic aortas from Gla^+/0 and Gla^−/0 mice in the presence of COX inhibitors with endothelium

	−log EC50, M
	Gla+/0	Gla−/0
Control	8.03±0.04 (8)	7.82±0.03† (10)
Indomethacin	8.38±0.05*(10)	8.09±0.03†‡ (10)
Valeryl salicylate	8.14±0.03 (8)	7.91±0.03† (8)
NS-398	8.36±0.06*(8)	8.06±0.05†‡ (8)

Values are means ± SE for the number of animals in parentheses. SNP, sodium nitroprusside.

^*P < 0.05 vs. Gla^+/0 control (by 1-way ANOVA with Newman-Keuls multiple comparison post hoc test).

^†P < 0.05 vs. Gla^+/0 in respective treatment group (by unpaired t-test).

^‡P < 0.05 vs. Gla^−/0 control (by 1-way ANOVA with Newman-Keuls multiple comparison).