Fig. 5.

Lack of effect of translocon inhibitors on Ca²⁺ release evoked by physiological agonists. All graphs show measurement of intracellular Ca²⁺ from VSMCs in the absence of extracellular Ca²⁺ (0 Ca²⁺). Data in A and B are each from single paired-independent experiments. A: effect of endothelin-1 (100 nM) after pretreatment with vehicle control (a) or 40 μM emetine (b) for 1 h. B: effect of ATP (100 μM) after pretreatment with vehicle control (a) or 400 μM anisomycin (b) for 1 h.