Pulmonary gene transfer of HIMF alters in vivo hemodynamics. Vertical bars represent means ± SE of mPAP (A), PVR (B), RVESP (C), RVEDP (D), CO (E), and LVEDP (F) in rats 35 days after treatment with vehicle or AAV-HIMF (5 × 1010 VP). The number of rats studied is indicated within each bar. *P < 0.05, **P < 0.01 compared to simultaneous control.