Figure 6.
Biological and antiviral comparison of α-HGA and some structurally related compounds. Chemical structures of glycine, glycineamide (G-NH2), α-HGA, oxamic acid, oxamide, α-methoxy glycineamide and Boc-α-methoxy glycineamide (A). Antiviral activity of 100 μM of respective compound added to HIV-1 SF-2 infected H9 cells cultured in the presence of 10% fetal bovine serum (B). Dose response of the antiviral activity of synthetically produced α-HGA (C).