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Comparison of Tsc2+/- mTOR inhibitor trials
| mTOR inhibitor | Total drug dose (per mouse) | Schedule | % Reduction in kidney tumors | Study |
| Rapamycin | 19.2 mg | Part one: 8 mg/kg daily × 1 month | 94.5%* | This study |
| Part two: 16 mg/kg weekly × 5 months | ||||
| Part three: 8 mg/kg daily × 1 month | ||||
| CCI-779 | 9.6 mg | 8 mg/kg daily × 2 months | 63%* | Messina et al. 2007 |
| 64%** | ||||
| CCI-779 | 4.32 mg | 4 mg/kg 3 times a week × 3 months | 83.6%** | Lee et al. 2005 |
* Kidney tumor score
**Kidney tumor number
